Contact: Department of Medical Laboratory Science, Igbinedion University, Okada, Nigeria
Wood is among the world’s valuable resources as a raw material for industries, construction, and as furniture. Wood dust has been reported to have serious health implication like sinusitis, nasal congestion, and cancer in some cases and has been linked to genotoxins from active component of a wood dust (Celik and Kanik, 2006). In order to assess the risks of occupational exposure in the different workforce, human biomonitoring methods were introduced to provide information on health-related changes in human. One of the approaches in assessing occupational health risks is the micronucleus (MN) assays (Celik and Kanik, 2006). Micronuclei (MNi) reflect structural and numerical chromosomal aberrations with a postulation that increased frequencies of MNi in lymphocytes are associated with cancer risks (Norppa and Falck, 2013). As far as we know there are limited studies on the effect of wood dust in saw-millers in this part of the world. Micronuclei, which are indicative of genotoxicity, were examined in peripheral blood film and buccal smear of saw-millers occupationally exposed to genotoxins in wood dust commonly called saw dust in Benin City, Nigeria.
Keywords: Binucleated cells, genotoxins, micronucleus, occupational exposure, and saw-dust