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Chitomask: An Innovative Intervention for Mitigation of Inhalation and OccupationalToxicology

Presentation Type: Oral 2016

Submission ID: 35 Name:Prof. Humphrey B. Contact: osaretin.igharo@uniben.edu, +2348038664896
Contributing Authors: Igharo, O.G.*, Osadolor, H. B., Emokpae, M.A. and Ikeke, K.I.

Category: CMS
Faculty: Basic Medical Science
Department: Department of Medical Laboratory Sciences
Address: Department of Chemical Pathology, Toxicology and Micronutrient Metabolism Unit, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Specialization:
Keywords: Chitosan
Submission date: 2018-08-28 16:20:40

Abstract

Chitosan is obtained from the deacetylation of chitin. Chitin is one of the most abundantly available polymers after cellulose. Chitosan is a copolymer of glucosamine and N-acetylglucosamine and it has an amine functional group which is strongly reactive with metal ions. Considerable research has been done on the uptake of metal cations by chitosan, (Rhazi, 2002).Chitin is an abundant organic material found mostly in crustaceans, mollusks and insects where it forms a constituent of the exoskeleton, (Guibal, 2004). It is also represented in fungal cell walls. Chitosan is therefore a copolymer of glucosamine and N-acetyl glucosamine, (Rojas, 2005). It is composed of β-(1 4)-2- amino-2-deoxy-D-glucopyranose (glucosamine units) and β-(1 4)-2-acetamido-2-deoxy-Dglucopyranose (acetylglucosamine units),(Hamdine, 2005). The term “chitosan” refers to chitin that has been deacetylated to greater than 60%. Chitosan has many properties that have generated interest in its use such as biodegradability, biocompatibility and its nontoxic nature, (Varma, 2004).


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